Vector Blog

RNAi isn’t ready to be silenced

RNA interference (RNAi) is a therapeutic technology that blocks gene expression with either small interfering RNAs (siRNA) or microRNAs (miRNA). RNAi’s discovery was considered transformative enough to earn the 2006 Nobel Prize for Physiology or Medicine, but from the start the challenge of delivering RNA-silencing therapeutics to the right tissues has hobbled efforts to use [Read More]

The light side of drug delivery

Getting drugs where they need to be, and at the right time, can be more challenging than you think. Tumors, for example, tend to have blood vessels that are tighter and twistier than normal ones, making it hard for drugs to penetrate them. Despite decades of research on antibodies, peptides and other guidance methods, drug [Read More]

Who We are

The mission of the Technology and Innovation Development Office (TIDO) is to translate the excellence of the laboratory research and clinical care at Children’s Hospital Boston into lifesaving biomedical products, devices and procedures for the public benefit.

News and Events

Pfizer CTI is now conducting a call for proposals at Boston Children’s. Non confidential pre-proposals are due May 16, 2014!

The second cycle of the collaboration program between Shire and Boston Children’s, which provides funding and additional in kind resources to support the development of therapeutics for rare diseases, was officially launched on April 1.

TIDO reached new heights in fiscal year 2013 with respect to industry partnerships, collaborations and licenses. 34 license and option agreements were executed, an increase of 13 percent over FY12, and 29 corporate sponsored and collaboration research agreements were executed, an increase of 45 percent over FY12. The report highlights selected licenses and collaborations, Technology Development Fund award winners, and selected technologies available for licensing.

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