Vector Blog

Mutations accumulate in our brain cells as we age. Do they explain cognitive loss?

Scientists have long wondered whether somatic, or non-inherited, mutations play a role in aging and brain degeneration. But until recently, there was no good technology to test this idea. Enter whole-genome sequencing of individual neurons. This fairly new technique has shown that our brain cells have a great deal of DNA diversity, making neurons somewhat...

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Routing gene therapy directly into the brain

A therapeutic technique to transplant blood-forming (hematopoietic) stem cells directly into the brain could herald a revolution in our approach to treating central nervous system diseases and neurodegenerative disorders. The technique, which could be used to transplant donor-matched hematopoietic stem cells (HSCs) or a patient’s own genetically-engineered HSCs into the brain, was reported in Science...

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TIDO is proud to announce the release of our new Inventor’s Guide. The booklet details the commercialization process at Boston Children’s, how to work with TIDO to give your invention the best possibility for success, and answers to frequently asked questions we encounter.

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