Technology Development

Proof of Concept Grant (POCG)

The POCG is awarded annually and provides up to $50,000 to advance early stage technologies in the validation or proof of concept phase. The award adds value to the technology to increase the probability of licensing. The application process begins by submitting a Letter of Intent (.doc). Successful applications are invited to submit a Full Proposal (.doc), as well as a brief presentation to an external advisory board. The grant can be used for:

  • Prototype development
  • Biological target validation and screening
  • Assay, reagent, or animal model development
  • Software optimization
  • Other advanced pre-commercial research

A minimum of 70 percent of the project will be performed by a contract research organization (CRO). The project must be completed within two years of the award date.


  • The application must be based on Intellectual Property (IP) developed at Boston Children's Hospital with the rights assigned to Boston Children's Hospital. The principal investigator must be a Boston Children's Hospital employee.
  • For the application to be considered for evaluation, a complete invention disclosure must be on file with TIDO or submitted along with the letter of intent.

Evaluation Criteria

Internal and external reviews are based on the following criteria:

  • Medical need or research significance
  • Path to market
  • Impact of grant
  • Technical feasibility
  • Freedom to operate
  • Stage of development

Guidelines for submission of the Letter of Intent

Guidelines for submission of Full Proposal and Presentation

  • Selected applicants will be invited to submit the full proposal. Download the Full Proposal (.doc), and submit as indicated for the LOI.*
  • Prepare a brief 15 minute presentation for the external advisory board. It is recommended that applicants follow the presentation guidelines provided with the full proposal.
  • Applicants chosen to receive funding will prepare and submit a project plan.

*Considering that the evaluation and selection process will place a strong emphasis on the commercial potential of the proposed project, applicants are encouraged to contact the technology development fund (please see contact info below) to discuss the full proposal as well as the format and content of the presentation.

Schedule and Deadlines:

  • TDF circulates the request for proposal (RFP) on January 16, 2018.
  • The LOI is due by 5 p.m. on February 12, 2018.
  • The applicants receive feedback by early April 2018.
  • The full proposal is due in late April 2018.
  • The final presentation slides are due May 2018.
  • The presentation to the advisory board: June 19th, 2018.
  • The funds will be disbursed on: to be announced.

Contact Information

For additional information, contact Carla Haslauer, PhD, Principal, and Monique Yoakim-Turk, Partner, Technology Development Fund at, or at x41375.

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